Wednesday 22nd October 2008

08.00am Onwards
Registration

09.25-09.30
Welcome & Opening Remarks

SESSION 1:
OPENING PLENARY
Moderator: Pearay L. Ogra (Women and Children’s Hospital, Buffalo, New York, USA)

09.30-10.00
‘Lessons from earlier and existing mucosal vaccines: oral polio vaccines (OPV), rotavirus vaccines and rubella vaccines’
Pearay L. Ogra (Women and Children's Hospital, Buffalo, New York, USA)

10.00-10.30
‘What is the relevance of mucosal immunity in man?’
Martin Friede (WHO, Geneva, Switzerland)

10.30-11.00
‘Modern mucosal vaccines and adjuvants - an overview’
Jan Holmgren (University of Gothenburg, Sweden)

11.00-11.30
Coffee Break & Poster Set-Up

SESSION 2:
PLENARY CONTINUED
Moderator: Martin Friede (WHO, Geneva, Switzerland)

11.30-12.00
‘Rational mucosal vaccine design - dreams, genes and reality’
Greg Glenn and Alex von Gabain (IOMAI, USA / Intercell AG, Vienna, Austria)

12.00-12.30
‘Role of TLR signaling in driving mucosal IgA responses’
Martin Bachmann (Cytos Biotechnology AG, Zurich, Switzerland)

12.30-13.00
‘Mucosal tolerance and vaccines’
Jiri Mestecky (University of Alabama, Birmingham, Alabama, USA)

13.00-14.00
Lunch & Posters

SESSION 3:
MUCOSAL IMMUNIZATION
Moderator: Jan Holmgren (University of Gothenburg, Sweden)

14.00-14.30
‘Vaccine patch for travellers diarrhea: reinforcing the guardians of the enterocyte lipid rafts’
Greg Glenn (IOMAI Inc., Gaithersburg, Maryland, USA)

14.30-15.00
‘Novel approaches for measuring immune responses of cervical-vaginal T cells with potential application to mucosal vaccines’
Maria Manoussaka, Steven Prideaux, Olanike Animasaun and Martin Cranage (St George’s, University of London, UK)

15.00-15.30
‘Achieving vaginal immune responses through mucosal immunization’
Melissa M. Herbst-Kralovetz, Brooke Hjelm, Daaimah LaVigne, Jacki Kilbourne, Charles Arntzen, Qiang Chen and Hugh Mason (Arizona State University, Tempe, Arizona, USA)

15.30-15.50
‘Mucosal and systemic immune responses induced by transcutaneous immunization’
M. Martin-Matos, L. Ye, I. Skountzou, D. Alexis, P. Haun, J. Jacob, S.M. Kang and R.W. Compans (Emory University, Atlanta, Georgia, USA)

15.50-16.10
Tea Break & Posters

SESSION 4:
ENTERIC
Moderator: Eric Cox (Ghent University, Belgium)

16.10-16.40
‘Mucosal immunisation generates high avidity CTL compared to systemic immunisation and expression of IL-4-IL-13 by CTL can modulate T cell avidity’
C. Ranasinghe, A.J. Ramsey and I.A. Ramshaw (The Australian National University, Acton, ACT, Australia)

16.40-17.00
‘The F4 receptor, a new target to induce intestinal immunity against enteropathogens’
E. Cox, K. Rasschaert, P. Tiels, F. Verdonck and B. Goddeeris (Ghent University, Belgium)

17.10-17.30
‘Immunotherapeutic PMED DNA immunization in combination with antiretroviral drug therapy increases immune function and reduces virus replication in the gut-associated tissues of SIV-infected rhesus macaques’
Michael Murphey-Corb, Premeela Rajakumar, Jenny Che, Brendon Whalberg, Heather Michael, Peter Ertl, Fiona Cook, Rachel Taber, Julia Nyuandi, John Tite and Deborah H. Fuller (University of Pittsburgh, Pennsylvania, USA)

17.30-18.00
Keynote Lecture:
‘Stimulating immunity to HIV at the virus portal of entry’
Martin Cranage (St.George’s, University of London, UK)

18.00-19.30
MMVAM 2008 Welcome Reception & Poster Session