Thursday 23rd October 2008

SESSION 5:
MICROBICIDES
Moderator: Kevin Whaley (Mapp Biopharmaceuticals Inc., USA)

09.00-09.30
‘Clinical Status of microbicides’
Kevin Whaley (Mapp Biopharmaceutical Inc., San Diego, California, USA)

09.30-10.00
Keynote Lecture:
‘HIV microbicides’
Charles Kelly (King’s College London, UK)

10.00-10.20
‘Development of a live mucosal microbicide for women’
Qiang Xu, Xiaowen Liu, Laurel A. Lagenaur, Yang Liu, Rosa Yu, Andrew Cheng, Kim Wells, Jun Wang, Thomas P. Parks, Dean H. Hamer and Peter P. Lee (Osel Inc., Santa Clara, California, USA)

10.20-10.40
‘Preventing sexual transmission of HSV and HIV: Manufacturing mapp66’
L. Zeitlin, N. Bohorova, D. Kim, J. Velasco, P. Bettinger, A. Hiatt, M. Pauly and K.J. Whaley (Mapp Biopharmaceutical Inc., San Diego, California, USA)

10.40-11.00
Coffee Break & Posters

SESSION 6:
TRANSGENICS & PLANT-BASED VACCINES
Moderator: Martin Cranage (St. George’s, London, UK)

11.00-11.30
Keynote:
‘Transgenic rice expressing vaccine antigens’
Hiroshi Kiyono (The University of Tokyo, Japan)

11.30-11.50
‘Immunogenic properties of plant-derived recombinant smallpox vaccine candidate pB5’
M. Golovkin, S. Spitsin, C. Portocarrero, K. Markley and H. Koprowski (Thomas Jefferson University, Philadelphia, USA)

11.50-12.10
‘Biochemical and immunological characterization of the plant-derived candidate HIV-1 mucosal vaccine CTB-MPR_649-684’
Nobuyuki Matoba, Hiroyuki Kajiura, Irene Cherni, Jeffrey Doran, Morgane Bomsel, Kazuhito Fujiyama and Tsafir S. Mor (Arizona State University, Tempe, Arizona, USA)

12.10-12.30
‘Expression of HIV epitope on the surface of a plant virus coat protein towards vaccine development’
D. Subha and R. Usha (Madurai Kamaraj University, Madurai, India)

12.30-13.00
Keynote:
‘Plant vaccines: current development’
Yasmin Thanavala (Roswell Park Cancer Institute, Buffalo, New York, USA)

13.00-14.00
Lunch & Posters

SESSION 7:
VACCINATION & ADJUVANTS
Moderator: Pearay L. Ogra (Buffalo, New York, USA)

14.00-14.30
Keynote:
‘Sublingual vaccination: cellular and molecular basis’
Cecil Czerkinsky (International Vaccine Institute, Seoul, Korea)

14.30-14.50
‘Adjuvants and formulations for sublingual allergy vaccines’
Laurence Van Overtvelt, Vincent Lombardi, Nathalie Saint-Lu, Alain Razafindratsita, Laurent Mascarell, Nathalie Berjont, Helene Moussu, Stephane Horiot and Philippe Moingeon (Stallergenes SA, Antony, France)

14.50-15.10
‘The use of cationic acyl-amines as adjuvants for nasal vaccines’
Ulf Schroder (Eurocine vaccines, Stockholm, Sweden)

15.10-15.30
‘Cationic polymers to optimize aerosol delivery of a Chlamyldophila posittaci DNA vaccine’
D. Vanrompay, K. Verminnen, N. Sanders and S. De Smedt (Ghent University, Belgium)

15.30-16.00
‘Pre-clinical and clinical models for evaluation of mucosal adjuvants and microbicides’
Alex Mann and Rob Lambkin-Williams (Retroscreen Virology Ltd., London, UK)

16.00-16.30
Tea Break & Posters

SESSION 8:
VACCINE CANDIDATES & DEVELOPMENT
Moderator: Cecil Czerkinsky (IVI, Seoul, Korea)

16.30-17.00
‘HIV vaccines - current developments’
Susan Barnett (Novartis Vaccines, Cambridge, Massachusetts, USA)

17.00-17.20
‘Induction of broadly reactive mucosal immunity by oral delivery of a multivalent HIV vaccine’
Ali Azizi (Variation Biotechnologies Inc., University of Ottawa, Canada)

17.20-17.40
‘Immunostimulation reconstituated influenza virosomes for vaginal immunization against Candida albicans’
Rinaldo Zurbriggen (Pevion Biotech Ltd., Bern, Switzerland)

17.40-18.00
‘Low-dose influenza ISCOMATRIC™ vaccine induces systemic and mucosal immunity following intrapulmonary delivery’
Jean-Pierre Y. Scheerlinck, Janet Wee, Ken Snibson, Stirling Edwards, Martin Pearse and Philip Sutton (The University of Melbourne/CSL Limited, Melbourne, Victoria, Australia)

18.00-18.20
‘Mucosal vaccines and biodefense: Lessons from RiVax™’
Nicholas J. Mantis and Robert Brey III (New York State Department of Health, Albany, New York, USA)

Free Evening for Delegates